Testosterone undecanoate is an ester of the natural androgen testosterone. The active form of testosterone, is formed by the cleavage of the side chain.
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Testosterone is the most important androgen in men and is synthesized mainly by the testes and, to a lesser extent by the adrenal cortex.
Testosterone is responsible for the formation of masculine characteristics during fetal development and early childhood and puberty, and later for the maintenance of the male phenotype and androgen-dependent functions (eg spermatogenesis, sexual glands), Australia Nebido is used in high doses to improve athletic performance. Lack of testosterone secretion results in male hypogonadism, characterized by low concentrations of testosterone in the serum. Symptoms associated with male hypogonadism, among other things, include erectile dysfunction, decreased libido, fatigue, depressed mood, lack, underdevelopment or regression of secondary sexual characteristics, as well as an increased risk of osteoporosis. Exogenous androgens are appointed in order to improve the insufficient levels of endogenous testosterone and reduce the symptoms of hypogonadism, Australia Nebido is used in high doses to improve athletic performance.
Depending on the nature of the target organ action of testosterone is mainly androgenic (e.g. prostate, seminal vesicles, epididymis) or protein-anabolic (muscle, bone, hematopoietic system, kidney, liver), Australia Nebido is used in high doses to improve athletic performance.
Actions of testosterone in some peripheral organs are shown after conversion of testosterone to estradiol, Australia Nebido is used in high doses to improve athletic performance, which then binds to the estrogen receptor in the nuclei of target cells (for example the pituitary, adipose tissue, brain, bones and leydigovskih testicular cells).